Treatments & Safety

Two major ways:
Delivery: Oestra™ is a vaginal cream, allowing for faster absorption and more stable hormone levels than oral pills or topical patches.

Formulation: It’s an all-in-one treatment. One pump a day delivers estradiol, progesterone, and testosterone (via conversion), saving you from juggling 4–6 separate prescriptions.

Oestra™ uses bioidentical hormones, which are derived from plant sources and designed to closely match the hormones your body naturally produces. While technically created in a lab, bioidentical hormones are widely considered a more natural and body-friendly option than synthetic alternatives.

Oestra™ was designed to be a safer, more effective, and easier-to-use hormone therapy—without the compromises.

Here’s what sets it apart:

  • Plant-based, bioidentical hormones that mimic the ones your body naturally makes
  • Targets your most bothersome symptoms, like hot flashes, brain fog, mood swings, and low libido
  • Doctor-supervised care from providers trained in women’s hormones
  • Easy-to-use, daily vaginal cream —no pills, patches, or injections
  • No lab work required to start, and no in-person visits
  • Shipped in 3-month supplies for convenience and consistency
  • Transparent pricing with no surprise fees

Our goal is to offer a treatment that’s not just effective, but also supportive and sustainable—so you can feel like yourself again.

Yes. Oestra™ contains estradiol and progesterone—bioidentical hormones that are FDA-approved for use in treating hormone deficiency. It’s also delivered vaginally, a method backed by over 100 high-quality studies showing stable hormone levels, systemic benefits, and protection of the uterine lining. Safety isn’t just a promise—it’s clinically supported.

It goes beyond that. Oestra™ is made by a 503A FDA-regulated compounding pharmacy that’s inspected by the FDA, DEA, and state licensing boards. Every prescription batch undergoes rigorous potency, purity, and safety checks before it ever reaches your door.

Yes, when they’re held to the highest regulatory standards—as ours is. Our partner pharmacy is LegitScript-certified, meaning it meets stringent quality and safety criteria. You’re getting the best of medicine with pharmaceutical-grade oversight.

Yes. Herbal supplements may temporarily ease symptoms, but they can’t restore hormone levels. Your body doesn’t make Dong Quai or Chaste Berry—it makes hormones. Oestra™ gives your body what it actually needs, in the correct ratios, with prescription-level quality and precision.

Hormones fluctuate constantly—sometimes by the hour. That’s why a single lab test rarely reflects your true needs. Instead of chasing numbers, we start with your symptoms—what you’re feeling in real life—and fine-tune from there. It’s faster, more personal, and far more effective. You’re not a lab value. You’re a whole person, and that’s how we treat you.

Absolutely—yes.

Our Menopause OestraTM formulation is designed specifically for menopausal women to give systemic results through vaginal delivery. In menopause, your ovaries produce almost no estrogen or progesterone—so systemic absorption is essential for symptom relief and long-term health (brain, bones, metabolism, mood, libido).

In most cases, no—neither. Women can experience hormone decline—and symptoms—long before menopause.
If you have:

  • anxiety
  • fatigue
  • PMS/PMDD
  • heavy or painful periods
  • low libido
  • sleep problems
  • mood changes
  • weight changes

…you may already have low hormones. Supporting them early is often preventative. On the other hand, even women in their 60s can safely begin HRT with proper screening and the right formulation. It’s never “too late” to protect bone, brain, heart metabolic and genitourinary health. The right time for HRT is when your symptoms show you need support.

Yes.
Oestra™ can be used alongside both:

  • hormonal IUDs(like Mirena®, Kyleena®)
  • non-hormonal IUDs(like the copper IUD)

A hormonal IUD mainly affects the uterus—not your systemic hormone levels.

Oestra™ works systemically through vaginal absorption into the bloodstream, so the two do not conflict. If you have specific concerns or symptoms related to your IUD, our clinicians can review them with you.

It is safe, but not advised. Oral birth control pills suppress ovulation and lower the production of your natural hormones, but bind to hormone receptors. Oestra™ can provide systemic support but needs to bind to the same receptors to work. We recommend an IUD, which has a more local effect, if birth control is desired.

Yes—Oestra™ is safe to use while breastfeeding.

Current evidence shows that bioidentical hormone therapy does not reduce milk supply, and many breastfeeding women choose to use Oestra™ for mood, sleep, libido, and overall hormonal support. We do recommend waiting 6 weeks postpartum before starting, simply to allow your milk supply to fully establish. If you have questions about timing or dosing, our clinicians are here to guide you.

No—bioidentical hormone therapy does not cause breast cancer.
This is one of the most pervasive myths in women’s health. Modern research and the FDA have clarified that the original concerns came from outdated studies using:

  • synthetic progestins (not bioidentical progesterone)
  • non-bioidentical estrogens
  • inappropriate populations

Bioidentical, body-identical hormones—most likely do not increase breast cancer risk and may, in some cases, be protective.

See here for FDA’s updated announcement and guidance.

Getting Prescribed

Start by taking our health quiz. If you’re a candidate, you’ll move straight to checkout. After a board-certified provider reviews your info, your custom prescription is sent to the pharmacy and shipped directly to you.

Every Oestra™ prescription is reviewed and approved by a licensed clinician. You don’t need a separate appointment—your quiz helps us determine if you’re a good fit to begin safely.

We don’t isolate hormones—we balance them. Most HRT programs target estrogen, progesterone, or testosterone in isolation. Oestra™ is different. It supports all three hormones together in the right ratios, to restore balance without the usual trial-and-error or side effects.

If you’re experiencing fatigue, brain fog, anxiety, irregular cycles, or changes in skin, sleep, mood, or weight—it’s time. You don’t need to wait until your period stops or hot flashes hit. Hormone decline starts years earlier, and the sooner you start, the more protected and vibrant you’ll feel.

Product Use

Apply one pearl-sized pump of cream daily to vaginal tissue—using your finger. It doesn’t need to be inserted deeply. Absorption through this tissue supports whole-body hormone balance.

You may start noticing changes within the first 2–4 weeks—especially around mood, sleep, and vaginal dryness. Deeper shifts like energy, skin, and metabolism take longer, often 3–6 months or more. Oestra™ isn’t a quick fix; it’s a full-body recalibration. But when balance returns, it’s worth the wait.

BodyMatched™ Face Cream

BodyMatched™ Anti-Aging Face Cream is a physician-formulated, prescription-strength topical therapy designed to address the visible signs of aging in hormonally shifting skin. It combines bioidentical estriol and a high-performance anti-aging complex of clinically proven actives to support collagen, hydration & skin texture.

This version of the cream is designed to reduce facial hair, fade dark spots, smooth wrinkles, and boost collagen. It includes topical finasteride in addition to estriol and tretinoin to target DHT-related skin changes.

Yes. These two products work on completely different systems of the body and can be safely used together. BodyMatched™ works locally on the skin of the face and neck. Oestra™ works systemically to support hormonal balance throughout the body. There is no interaction between them, and many women use both for comprehensive skin and hormone support.

This prescription-only formula combines hormone-informed care (like estriol and finasteride) with clinically proven dermatological actives (like tretinoin), delivering results beyond what you’ll find in over-the-counter anti-aging products.

Estriol is a gentle, bioidentical estrogen that helps increase collagen, hydrate dry skin, and reduce fine lines. It’s especially helpful for peri- and postmenopausal women.

Topical finasteride blocks DHT, a hormone that contributes to unwanted facial hair, oily skin, and enlarged pores. It helps smooth skin and reduce hair growth without major systemic side effects.

Tretinoin boosts cell turnover, smooths wrinkles, treats acne, and improves texture. It’s one of the most studied and effective ingredients in prescription anti-aging skincare.

No—it helps reduce the thickness, darkness, and growth rate of unwanted facial hair over time. Most women experience finer, softer hair, not total removal.

Yes. Finasteride and niacinamide (included in the formula) help reduce oil production, shrink pores, and calm inflammation—making the cream helpful for women with acne-prone or oily skin.

You may experience slight dryness, redness, or peeling in the first few weeks—especially from tretinoin. These effects are usually temporary and improve as your skin adjusts. Daily sunscreen is recommended.

Yes. The dose and combination are well-tolerated by sensitive skin. If you’re extra sensitive, start with every other day for a few weeks. Mild irritation may occur at first but typically resolves with consistent use.

Yes. This cream is available by prescription only and is customized for you by Inner Balance clinicians. You’ll complete a short evaluation to ensure it’s appropriate for your skin and health history.

You’ll have unlimited access to our clinical care team for follow-up support. Whether you’re experiencing irritation or just want to track progress, our licensed providers are here to help.

Start with once nightly. If your skin is sensitive, begin every other day and increase frequency gradually. Always follow with sunscreen in the morning.

You may notice increased hydration and smoother texture in 2–4 weeks. Wrinkle reduction and hair thinning typically take 8–12 weeks, with best results at 3–6 months of consistent use.

Yes—but avoid other retinoids or exfoliants (like scrubs or acids) while your skin adjusts. Keep your routine simple and always use SPF during the day.

Avoid direct application to eyelids or the lash line. It’s safe to use around the orbital bone unless otherwise directed by your Inner Balance clinician.

Eligibility & Access

Not at all. We work with women as young as 21. In fact, many women start in their 30s or 40s—often before traditional medicine recognizes hormone decline. The earlier you begin, the more protection you provide your bones, brain, heart, skin, and metabolism.

It’s not—but that’s often a good thing. Insurance typically only covers the most limited options. Oestra™ replaces 5–6 prescriptions and is still more cost-effective than most HRT plans. We also offer referral discounts and 6-month satisfaction guarantees.

Yes. As long as it’s within six months of starting treatment, we’ll honor a full refund if you’re not satisfied. We may ask a few supportive questions first to make sure there’s nothing we can adjust to help you feel better.

Yes we do accept HSA and FSA payments! Learn more about using your HSA/FSA here.

Shipping & Delivery

Yes! Shipping is always free. Your shipment includes a 3-month supply.

Once your prescription is approved, your prescription treatment is compounded and shipped within 3–5 business days. You’ll receive tracking details by SMS once your order is on its way.

Most U.S. orders arrive within 3–5 business days after shipment. We’ll send tracking info so you can follow along.

You’ll receive a 3-month supply of Oestra™ with each shipment. We bill monthly, and your subscription includes unlimited clinician messaging, check-ins, and refill coordination.

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